Acute abdomen due to intestinal angioedema induced by ACE inhibitors : not so rare ?

During the last 5 years we identified 7 patients with a history of episodic acute abdominal pain and subobstruction due to intestin- al angioedema secondary to the use of Angiotensin Converting Enzyme (ACE) inhibitors. These cases were all diagnosed in one gastroenterology department. This is thereby the largest single cen- tre case series of ACE inhibitor-induced angioedema that has been published until now. Our findings suggest that this syndrome is far more frequent than international literature would let us believe. We also describe one of the first male cases diagnosed with this entity for which there is a significant female predominance. In the presence of an appropriate history and suggestive findings on CT scan, this diagnosis can relatively easily be made if one is sufficient- ly intent on it. An appropriate diagnosis can save these patients a lot of unnecessary diagnostic procedures and discomfort. (Acta gastroenterol. belg., 2009, 72, 455-457).